Background

The Laboratory of Applied Pharmacokinetics (LAPK) of the Keck School of Medicine at the University of Southern California is a resource for optimal study and control of pharmacokinetic systems and for individualized drug therapy. It is supported by The National Institute for General Medical Studies (GM068968), and the National Institute of Biomedical Imaging and Bioengineering (EB005803). [More...]

Research activities

Current research activities include: Application of stochastic control theory to the design of optimal dosage regimens; improved methods for population pharmacokinetic modeling; investigation of process and measurement noise in the clinical environment; evaluation of alternative parameterizations of pharmacokinetic models; optimal monitoring strategies for pharmacokinetic studies, clinical trials, and patient care; and development of clinically reliable interfaces and apparatus for delivering complex drug infusion regimens. [More...]

Education and training activities

Dissemination of the concepts and capabilities of this laboratory to other research institutions and to industry is carried out through workshops, short courses, technical reports, symposia, fellowships, and scientist-in-residence programs. Further information can be obtained by writing directly to the laboratory. [More...]